Scientific publications

Aits S. Methods to detect loss of lysosomal membrane integrity. Methods in Molecular Biology 2019; 1880:315-329.

Pagliero RJ, D'Astolfo DS, Lelieveld D, Pratiwi RD, Aits S, Jaattela M, Martin NI, Klumperman J, Egan DA. Discovery of Small Molecules That Induce Lysosomal Cell Death in Cancer Cell Lines Using an Image-Based Screening Platform. ASSAY and Drug Development Technologies 2016; 14: 489-510.

Aits S, Jaattela M, Nylandsted J. Methods for the quantification of lysosomal membrane permeabilization: a hallmark of lysosomal cell death. Methods in Cell Biology 2015; 126: 261-85.

Aits S, Kricker J, Liu B, Ellegaard AM, Hamalisto S, Tvingsholm S, Corcelle-Termeau E, Hogh S, Farkas T, Holm Jonassen A, Gromova I, Mortensen M, Jaattela M. Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay. Autophagy 2015; 11: 1408-24.

Aits S and Jaattela M. Lysosomal cell death at a glance. Journal of Cell Science 2013; 126: 1905-12.

Groth-Pedersen L*, Aits S* (* shared first authorship), Corcelle-Termeau E, Petersen NH, Nylandsted J, Jaattela M. Identification of cytoskeleton-associated proteins essential for lysosomal stability and survival of human cancer cells. PLoS One 2012; 7: e45381.

Storm P, Aits S, Puthia MK, Urbano A, Northen T, Powers S, Bowen B, Chao Y, Reindl W, Lee DY, Sullivan NL, Zhang J, Trulsson M, Yang H, Watson JD, Svanborg C. Conserved features of cancer cells define their sensitivity to HAMLET-induced death; c-Myc and glycolysis. Journal of Computer Science and Systems Biology 2012; 5(1): 187

Storm P*, Aits S* (* shared first authorship), Puthia MK*, Urbano A, Northen T, Powers S, Bowen B, Chao Y, Reindl W, Lee DY, Sullivan NL, Zhang J, Trulsson M, Yang H, Watson JD, Svanborg C. Conserved features of cancer cells define their sensitivity to HAMLET-induced death; c-Myc and glycolysis. Oncogene 2011; 30: 4765-79.

Trulsson M, Yu H, Gisselsson L, Chao Y, Urbano A, Aits S, Mossberg AK, Svanborg C. HAMLET binding to alpha-actinin facilitates tumor cell detachment. PLoS One 2011; 6: e17179.

Gustafsson L, Aits S, Onnerfjord P, Trulsson M, Storm P, Svanborg C. Changes in proteasome structure and function caused by HAMLET in tumor cells. PLoS One 2009; 4: e5229.

Pettersson-Kastberg J, Aits S, Gustafsson L, Mossberg A, Storm P, Trulsson M, Persson F, Mok KH, Svanborg C. Can misfolded proteins be beneficial? The HAMLET case. Annals of Medicine 2009; 41: 162-76.

Aits S, Gustafsson L, Hallgren O, Brest P, Gustafsson M, Trulsson M, Mossberg AK, Simon HU, Mograbi B, Svanborg C. HAMLET (human alpha-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death. International Journal of Cancer 2009; 124: 1008-19.

Aits S, Gustafsson L, Gustafsson M, Mossberg A, Storm P, Trulsson M, Svanborg C. HAMLET kills tumor cells; structure, cellular targets and therapeutic agents, in Proteins Killing Tumour Cells Backendorf, C, Noteborn MHN, and Tavassoli M, Editors. Research Signpost: Kerala, India. 2009, p. 51-9.

Svanborg C, Aits S, Brest P, Gustafsson L, Mok KH, Moreillhon C, Mossberg AK, Pettersson J, Storm P, Trulsson M. HAMLET, a tumoricidal molecular complex from human milk. BMC Proceedings 2009; 3(Suppl 5): S11

Lindgren D, Gudjonsson S, Jee KJ, Liedberg F, Aits S, Andersson A, Chebil G, Borg A, Knuutila S, Fioretos T, Mansson W, Hoglund M. Recurrent and multiple bladder tumors show conserved expression profiles. BMC Cancer 2008; 8: 183.

Hallgren O, Aits S, Brest P, Gustafsson L, Mossberg AK, Wullt B, Svanborg C. Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells). Advances in Experimental Medicine and Biology 2008; 606: 217-40.

Lindgren D, Gudjonsson S, Liedberg F, Aits S, Andersson A, Chebil G, Knuutila S, Fioretos T, Mansson W, Hoglund M. Meta- and synchronous urothelial carcinomas with divergent genomic profiles show highly similar gene-expression profiles. European Urology Supplements 2006; 5(14): 804

General publications

Aits S. LibGuide: Cell Death, 2018, http://libguides.lub.lu.se/aitslab/celldeath

Aits S. LibGuide: Microscopy-Based High-Content Screening (High-Content Imaging), 2018, http://libguides.lub.lu.se/aitslab/HCS

Aits S. LibGuide “Team Science”. 2018, http://libguides.lub.lu.se/aitslab/teamscience

Aits S. LibGuide “Laboratory Leadership and Management”. 2018, http://libguides.lub.lu.se/aitslab/lableadership

Aits S, Englund E, Hansson N, Klasson H, Matthiesen L. Public presentation on Slideshare “Mentometer i undervisning”. 2018 (original presentation 2016), https://www.slideshare.net/SonjaAits/mentometer-i-undervisning-clickers-in-teaching

Youtube channel with six collections of tutorials for image analysis tools. 2018, https://www.youtube.com/channel/UCmh81PBL4lU6r6mcGqhRPbQ/playlists